Go PLR Content Directory Sierra Leone: September 2012

Wednesday 26 September 2012

AmeriPhor

Generic Name: topical emollients (TOP i kal ee MOL i ents)

Brand Names: Aloe Vesta Cream, AlphaSoft, AmeriPhor, Aqua Glycolic, Aqua Lube, Aquaphor, Aveeno, Baby Lotion, Baby Oil, Bag Balm, Baza-Pro, Beta Care, Blistex Lip Balm, Carmex, CarraKlenz, CeraVe, CeraVe AM, Cetaphil Lotion, Chap Stick, Citraderm, CoolBottoms, Corn Huskers Lotion, Curel Moisture Lotion, Derma Soothe, Dr Scholl's Essentials Cracked Skin Repair, Eucerin, Herpecin-L, K-Y Jelly, Keri Lotion, Lamisilk Heel Balm, Lubri-Soft, Lubriderm, Mederma, Moisturel, Natural Ice, NeutrapHor, NeutrapHorus Rex, Neutrogena Cleansing, Neutrogena Lotion, Nivea, Nutraderm, Pacquin, Phisoderm, Pretty Feet & Hands, Proshield Skincare Kit, Remedy 4-in-1 Cleansing Lotion, Replens, Secura, Sensi-Care, Soft Sense, St. Ives, Theraplex Lotion, Vaseline Intensive Care

What are AmeriPhor (topical emollients)?

Emollients are substances that moisten and soften your skin.

Topical (for the skin) emollients are used to treat or prevent dry skin. Topical emollients are sometimes contained in products that also treat acne, chapped lips, diaper rash, cold sores, or other minor skin irritation.

There are many brands and forms of topical emollients available and not all are listed on this leaflet.

Topical emollients may also be used for purposes not listed in this medication guide.

What is the most important information I should know about AmeriPhor (topical emollients)?

You should not use a topical emollient if you are allergic to it. Topical emollients will not treat or prevent a skin infection.

Ask a doctor or pharmacist before using this medication if you have deep wounds or open sores, swelling, warmth, redness, oozing, bleeding, large areas of skin irritation, or any type of allergy.

What should I discuss with my healthcare provider before using AmeriPhor (topical emollients)?

You should not use a topical emollient if you are allergic to it. Topical emollients will not treat or prevent a skin infection.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have:

deep wounds or open sores;

swelling, warmth, redness, oozing, or bleeding;

large areas of skin irritation;

any type of allergy; or

if you are pregnant or breast-feeding.

How should I use AmeriPhor (topical emollients)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Clean the skin where you will apply the topical emollient. It may help to apply this product when your skin is wet or damp. Follow directions on the product label.

Shake the product container if recommended on the label.

Apply a small amount of topical emollient to the affected area and rub in gently.

If you are using a stick, pad, or soap form of topical emollient, follow directions for use on the product label.

Do not use this product over large area of skin. Do not apply a topical emollient to a deep puncture wound or severe burn without medical advice.

If your skin appears white or gray and feels soggy, you may be applying too much topical emollient or using it too often.

Some forms of topical emollient may be flammable and should not be used near high heat or open flame, or applied while you are smoking.

Store as directed away from moisture, heat, and light. Keep the bottle, tube, or other container tightly closed when not in use.

What happens if I miss a dose?

Since this product is used as needed, it does not have a daily dosing schedule. Seek medical advice if your condition does not improve after using a topical emollient.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking AmeriPhor (topical emollients)?

Avoid getting topical emollients in your eyes, nose, or mouth. If this does happen, rinse with water. Avoid exposure to sunlight or tanning beds. Some topical emollients can make your skin more sensitive to sunlight or UV rays.

AmeriPhor (topical emollients) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using the topical emollient and call your doctor if you have severe burning, stinging, redness, or irritation where the product was applied.

Less serious side effects are more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect AmeriPhor (topical emollients)?

It is not likely that other drugs you take orally or inject will have an effect on topically applied products. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More AmeriPhor resources

AmeriPhor Use in Pregnancy & Breastfeeding
AmeriPhor Support Group
0 Reviews for AmeriPhor - Add your own review/rating

Biafine Emulsion MedFacts Consumer Leaflet (Wolters Kluwer)

Campath Monograph (AHFS DI)

Campral Monograph (AHFS DI)

Camptosar Monograph (AHFS DI)

Diabinese Monograph (AHFS DI)

Kinerase Cream MedFacts Consumer Leaflet (Wolters Kluwer)

Neosalus Foam MedFacts Consumer Leaflet (Wolters Kluwer)

Promiseb Cream MedFacts Consumer Leaflet (Wolters Kluwer)

Compare AmeriPhor with other medications

Dry Skin

Where can I get more information?

Your pharmacist can provide more information about topical emollients.

Monday 24 September 2012

Citrucel SF

Generic Name: methylcellulose (METH il SEL yoo los)

Brand Names: Citrucel, Citrucel Clear Mix, Citrucel Food Pack, Citrucel Lax, Citrucel SF

What is Citrucel SF (methylcellulose)?

Methylcellulose is a bulk-forming laxative. Methylcellulose absorbs liquid in the intestines and makes a bulky, softer stool which is easier to pass.

Methylcellulose helps relieve constipation and to maintain regularity.

Methylcellulose may also have uses other than those listed in this product guide.

What is the most important information I should know about Citrucel SF (methylcellulose)?

Do not use methylcellulose without first talking to your doctor if you have stomach (abdominal) pain, nausea, vomiting, or difficulty swallowing. Taking methylcellulose without enough liquid may cause it to swell in the throat and cause choking. If you experience chest pain, vomiting, difficulty swallowing, or difficulty breathing after taking methylcellulose, seek immediate medical attention.

What should I discuss with my healthcare provider before taking Citrucel SF (methylcellulose)?

Do not take methylcellulose without first talking to your doctor if you have

stomach (abdominal) pain, nausea, or vomiting;

difficulty swallowing; or

intestinal obstruction or fecal impaction.

You may not be able to take methylcellulose or you may require special monitoring while taking methylcellulose if you have any of the conditions listed above.

Each level scoop of sugar-free methylcellulose powder contains 52 mg of phenylalanine. Individuals with phenylketonuria may need to monitor their intake of this additive.

Talk to your doctor before taking methylcellulose if you are pregnant or breast-feeding a baby.

How should I take Citrucel SF (methylcellulose)?

Take methylcellulose exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take methylcellulose capsules with a full glass (at least 8 ounces) of water or another liquid.

Mix methylcellulose powder with at least 8 ounces of water or another noncarbonated beverage. Mix briskly and drink promptly.

Taking methylcellulose without enough liquid may cause it to swell in the throat and cause choking.

If methylcellulose has produced no effect within one week or if rectal bleeding occurs, stop taking methylcellulose and contact your doctor. Do not take more methylcellulose than is recommended or for longer than one week except under the direction of your doctor.

If you experience chest pain, vomiting, difficulty swallowing, or difficulty breathing after taking methylcellulose, seek immediate medical attention. Store methylcellulose at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a methylcellulose overdose are not known.

What should I avoid while taking Citrucel SF (methylcellulose)?

There are no restrictions on foods, beverages, or activities during treatment with methylcellulose unless otherwise directed by your healthcare provider.

Citrucel SF (methylcellulose) side effects

If you experience any of the following uncommon but serious side effects, stop taking methylcellulose and seek medical treatment or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

chest pain;

difficulty swallowing;

rectal bleeding; or

severe abdominal pain, nausea or vomiting.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Citrucel SF (methylcellulose)?

Methylcellulose can interact with other medications. Before taking methylcellulose, talk to your doctor if you are taking any prescription or over-the-counter medicines. You may not be able to take methylcellulose, or you may require a dosage adjustment or special monitoring if you are taking any other medicines.

More Citrucel SF resources

Citrucel SF Side Effects (in more detail)
Citrucel SF Use in Pregnancy & Breastfeeding
Citrucel SF Drug Interactions
Citrucel SF Support Group
1 Review for Citrucel SF - Add your own review/rating

Citrucel Prescribing Information (FDA)

Citrucel MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Citrucel SF with other medications

Constipation

Where can I get more information?

Your pharmacist has more information about methylcellulose written for health professionals that you may read.

See also: Citrucel SF side effects (in more detail)

Wednesday 19 September 2012

Tomycine

Generic Name: tobramycin (Ophthalmic route)

toe-bra-MYE-sin

Commonly used brand name(s)

In the U.S.

AKTob

Tobrasol

Tobrex

In Canada

Apo-Tobramycin

Sab-Tobramycin

Tomycine

Available Dosage Forms:

Ointment

Solution

Therapeutic Class: Antibiotic

Chemical Class: Aminoglycoside

Uses For Tomycine

Ophthalmic tobramycin is used in the eye to treat bacterial infections of the eye. Tobramycin works by killing bacteria.

Ophthalmic tobramycin may be used alone or with other medicines for eye infections. Either the drops or the ointment form of this medicine may be used alone during the day. In addition, both forms may be used together, with the drops being used during the day and the ointment at night.

Tobramycin ophthalmic preparations are available only with your doctor's prescription.

Before Using Tomycine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

This medicine has been tested in children and, in effective doses, has not been shown to cause different side effects or problems than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of ophthalmic tobramycin in the elderly with use in other age groups.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	D	Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Alcuronium

Atracurium

Cidofovir

Cisatracurium

Colistimethate Sodium

Decamethonium

Doxacurium

Ethacrynic Acid

Fazadinium

Furosemide

Gallamine

Hexafluorenium

Lysine

Metocurine

Mivacurium

Pancuronium

Pipecuronium

Rapacuronium

Rocuronium

Succinylcholine

Tacrolimus

Tubocurarine

Vancomycin

Vecuronium

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Cisplatin

Cyclosporine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of tobramycin

This section provides information on the proper use of a number of products that contain tobramycin. It may not be specific to Tomycine. Please read with care.

For patients using tobramycin ophthalmic solution (eye drops):

The bottle is only partially full to provide proper drop control.

To use:
- First, wash your hands. Tilt the head back and with the index finger of one hand, press gently on the skin just beneath the lower eyelid and pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed for 1 or 2 minutes, to allow the medicine to come into contact with the infection.
- If you think you did not get the drop of medicine into your eye properly, use another drop.
- To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed.

If your doctor ordered two different ophthalmic solutions to be used together, wait at least 5 minutes between the times you apply the medicines. This will help to keep the second medicine from ``washing out'' the first one.

For patients using tobramycin ophthalmic ointment (eye ointment):

To use:
- First, wash your hands. Tilt the head back and with the index finger of one hand, press gently on the skin just beneath the lower eyelid and pull the lower eyelid away from the eye to make a space. Squeeze a thin strip of ointment into this space. A 1.25-cm (approximately ½-inch) strip of ointment usually is enough, unless you have been told by your doctor to use a different amount. Let go of the eyelid and gently close the eyes and keep them closed for 1 or 2 minutes, to allow the medicine to come into contact with the infection.
- To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). After using tobramycin eye ointment, wipe the tip of the ointment tube with a clean tissue and keep the tube tightly closed.

To help clear up your eye infection completely, keep using tobramycin for the full time of treatment, even if your symptoms have disappeared. Do not miss any doses.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For ophthalmic ointment dosage forms:
- For mild to moderate infections:
  - Adults and children—Use every eight to twelve hours.
- For severe infections:
  - Adults and children—Use every three to four hours until improvement occurs.

For ophthalmic solution (eye drops) dosage forms:
- For mild to moderate infections:
  - Adults and children—One drop every four hours.
- For severe infections:
  - Adults and children—One drop every hour until improvement occurs.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Tomycine

If your eye infection does not improve within a few days, or if it becomes worse, check with your doctor.

Tomycine Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Itching, redness, swelling, or other sign of eye or eyelid irritation not present before use of this medicine

Symptoms of overdose

Increased watering of the eyes

itching, redness, or swelling of the eyes or eyelids

painful irritation of the clear front part of the eye

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Burning or stinging of the eyes

Eye ointments usually cause your vision to blur for a few minutes after application.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Tomycine side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Tomycine resources

Tomycine Side Effects (in more detail)
Tomycine Use in Pregnancy & Breastfeeding
Tomycine Support Group
0 Reviews for Tomycine - Add your own review/rating

Aktob Concise Consumer Information (Cerner Multum)

Tobrex Prescribing Information (FDA)

Tobrex Drops MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Tomycine with other medications

Conjunctivitis, Bacterial

Tuesday 18 September 2012

Sodium Chloride Irrigation Baxter

Sodium Chloride Description

0.9% Sodium Chloride Irrigation, USP in the Baxter Sterile Container System is a sterile, nonpyrogenic, isotonic solution for the preparation of slushed solution. It contains no antimicrobial agents. Composition, osmolarity, pH and ionic concentration are shown in Table 1.

Table 1
	Size (mL)	Composition (g/L)	Osmolarity (mOsmol/L) (calc)	pH	Ionic Concentration (mEq/L)
	Size (mL)	Sodium Chloride, USP (NaCl)	Osmolarity (mOsmol/L) (calc)	pH	Sodium	Chloride
0.9 % Sodium Chloride Irrigation, USP	1000	9	308	5.0 (4.5 to 7.0)	154	154

The Baxter Sterile Container System is designed to provide a slush container with a sterile exterior surface for use within the surgical field. Within the overwrap, the unit is packaged in a dispensing bag which maintains the sterility of this surface.

The flexible plastic slush container is fabricated from a specially formulated polyvinyl chloride (PL 146 Plastic). The amount of water that can permeate from inside the container into the overwrap is insufficient to affect the solution significantly. Solutions in contact with the plastic container can leach out certain of its chemical components in very small amounts within the expiration period, e.g., di-2-ethylhexyl phthalate (DEHP), up to 5 parts per million. However, the safety of the plastic has been confirmed in tests in animals according to USP biological tests for plastic containers as well as by culture toxicity studies.

Sodium Chloride - Clinical Pharmacology

Slushed solution is used to induce regional hypothermia in conditions such as certain open heart and kidney surgical procedures by direct application of slushed solution. The objective of regional hypothermia is to reduce cellular metabolic activity so that body tissues can tolerate a period of total or relative ischemia thereby inhibiting the formation and buildup of destructive autolytic enzymes and anaerobic by-products usually produced and accumulated in ischemic tissues.

Indications and Usage for Sodium Chloride

Slushed solution is used to create regional hypothermia in order to reduce and minimize manifestations of warm-temperature ischemia. Temperature probes may be used to determine requirements for replacement or addition of slushed solution.

Contraindications

None known

Warnings

Not for injection. For use in slush preparation for regional hypothermia.

Precautions

Avoid prolonged direct contact between ice crystals and body tissues.

Experience in use of slushed solutions in pediatrics is limited.

Carcinogenesis and Mutagenesis and Impairment of Fertility

Studies performed with slushed 0.9% Sodium Chloride Irrigation, USP have not been performed to evaluate carcinogenic potential, mutagenic potential, or effects on fertility.

Pregnancy

Teratogenic Effects

Pregnancy Category C

Animal reproduction studies have not been conducted with slushed 0.9% Sodium Chloride Irrigation, USP. It is also not known whether slushed 0.9% Sodium Chloride Irrigation, USP can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Slushed 0.9% Sodium Chloride Irrigation, USP should be given to a pregnant woman only if clearly needed.

Nursing Mothers

It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when slushed 0.9% Sodium Chloride Irrigation, USP is administered to a nursing mother.

Pediatric Use

Safety and effectiveness of slushed 0.9% Sodium Chloride Irrigation, USP in pediatric patients have not been established by adequate and well controlled trials; however, the use of electrolyte solutions in the pediatric population is referenced in the medical literature. The warnings, precautions and adverse reactions identified in the label copy should be observed in the pediatric population.

Do not administer unless seals of outer dispensing bag are intact.

Adverse Reactions

No serious adverse reactions are known.

Sodium Chloride Dosage and Administration

The volume of slushed solution required will vary with patient’s age, clinical condition, cooling effect desired and duration of cooling effect desired, according to physician’s instructions.

How is Sodium Chloride Supplied

0.9% Sodium Chloride Irrigation, USP in the Baxter Sterile Container System is supplied as follows:

Code	Size (mL)	NDC	DIN
2B7231	1000	0338-0051-44	786160

Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. Avoid freezing except during controlled slushing procedure. It is recommended that this product be stored at room temperature (25ºC); brief exposure up to 40ºC does not adversely affect this product.

DIRECTIONS FOR USE OF THE BAXTER STERILE CONTAINER SYSTEM

Guidelines for Preparation of Slush

The following instructions are intended only as guidelines for the preparation of slush using the Baxter Sterile Container System. The specific procedure necessary to achieve the desired slush consistency will depend on the type of freezer used, location of the product in the freezer, and the utilization of freezer capacity.

Remove product from shipping carton and place in freezer at a temperature between minus 4ºC and minus 15ºC for 2 to 6 hours. Note: A pre-cooled product will require less time to slush.

During the freezing process, remove product from freezer periodically and carefully massage to break up large frozen chunks of solution.

Return product to freezer and repeat procedure until desired slush consistency is obtained.

To Open: Use Aseptic Technique

A. To prepare the unit outside of the surgical field

Tear overwrap down side at slit and remove dispensing bag which contains the slush container.

Allow unit to stand at room temperature for approximately 10 minutes to allow container material to regain flexibility.

Check that all the seals of the dispensing bag are intact including the tamper evident button. If any broken seals or holes are detected, discard unit as sterility may be impaired.

Grasp tab of dispensing bag and peel open (Figure 1). Remove wrapped inner slush container.

Grasp point of sterile transfer wrap (Figure 2), and pull forward then back to expose sterile slush container (Figure 3). Caution should be exercised to avoid touch contamination.

B. To transfer sterile slush container to the surgical field

Using sterile gloved hands, remove slush container from the sterile transfer wrap (Figure 4). Place on surgical field or use immediately.

Grasp tab at top of slush container and peel directly across the width of the container with a steady motion (Figure 5).

Slush is ready for dispensing.

Baxter Healthcare Corporation Deerfield, IL 60015 USA

Printed in USA

Distributed in Canada by Baxter Corporation Toronto, Ontario, Canada

07-19-04-501Rev. October 2003

BAXTER and PL 146 are trademarks of Baxter International Inc.

*Bar Code Position Only

071904501

SODIUM CHLORIDE
sodium chloride irrigant

Product Information
Product Type	HUMAN PRESCRIPTION DRUG	NDC Product Code (Source)	0338-0051
Route of Administration	IRRIGATION	DEA Schedule

INGREDIENTS
Name (Active Moiety)	Type	Strength
Sodium Chloride (sodium chloride)	Active	9 GRAM In 1 LITER
Water	Inactive

Product Characteristics
Color		Score
Shape		Size
Flavor		Imprint Code
Contains

Packaging
#	NDC	Package Description	Multilevel Packaging
1	0338-0051-44	1 L (LITER) In 1 BAG	None

Revised: 07/2006Baxter Healthcare Corporation

Sunday 16 September 2012

Augmentin Suspension

Pronunciation: a-MOX-i-SIL-in/KLAV-ue-la-nate
Generic Name: Amoxicillin/Clavulanate
Brand Name: Augmentin

Augmentin Suspension is used for:

Treating infections caused by certain bacteria.

Augmentin Suspension is a penicillin antibiotic. It works by killing sensitive bacteria.

Do NOT use Augmentin Suspension if:

you are allergic to any ingredient in Augmentin Suspension or another penicillin antibiotic (eg, ampicillin)

you have a history of liver problems or yellowing of the eyes or skin caused by Augmentin Suspension

you have infectious mononucleosis (mono)

you have recently received or will be receiving live oral typhoid vaccine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Augmentin Suspension:

Some medical conditions may interact with Augmentin Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have a history of allergies, asthma, hay fever, or hives

if you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties, dizziness) to a cephalosporin (eg, cephalexin) or another beta-lactam antibiotic (eg, imipenem)

if you have kidney problems or gonorrhea

if you have a history of liver problems or yellowing of the eyes or skin

Some MEDICINES MAY INTERACT with Augmentin Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticoagulants (eg, warfarin) because the risk of bleeding may be increased

Probenecid because it may increase the amount of Augmentin Suspension in your blood

Chloramphenicol, macrolide antibiotics (eg, erythromycin), sulfonamides (eg, sulfamethoxazole), or tetracycline antibiotics (eg, doxycycline) because they may decrease Augmentin Suspension's effectiveness

Methotrexate because the risk of its side effects may be increased by Augmentin Suspension

Live oral typhoid vaccine or hormonal birth control (eg, birth control pills) because their effectiveness may be decreased by Augmentin Suspension

This may not be a complete list of all interactions that may occur. Ask your health care provider if Augmentin Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Augmentin Suspension:

Use Augmentin Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Augmentin Suspension by mouth at the start of a meal to decrease the chance of stomach upset.

Shake well before each use.

Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.

To clear up your infection completely, take Augmentin Suspension for the full course of treatment. Keep taking it even if you feel better in a few days.

If you miss a dose of Augmentin Suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Augmentin Suspension.

Important safety information:

Augmentin Suspension may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Augmentin Suspension with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Augmentin Suspension only works against bacteria; it does not treat viral infections (eg, the common cold).

Be sure to use Augmentin Suspension for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

Long-term or repeated use of Augmentin Suspension may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

Hormonal birth control (eg, birth control pills) may not work as well while you are using Augmentin Suspension. To prevent pregnancy, use an extra form of birth control (eg, condoms).

Brown, yellow, or gray tooth discoloration has occurred rarely in some patients taking Augmentin Suspension. It occurred most often in children. The discoloration was reduced or removed by brushing or dental cleaning in most cases. Contact your doctor if you experience this effect.

Diabetes patients - Augmentin Suspension may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.

Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed if you use Augmentin Suspension for a long period of time. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Augmentin Suspension with caution in the ELDERLY; they may be more sensitive to its effects, especially patients with kidney problems.

Use Augmentin Suspension with extreme caution in CHILDREN younger than 10 years old who have diarrhea or an infection of the stomach or bowel.

Augmentin Suspension should be used with extreme caution in CHILDREN younger than 3 months old; safety and effectiveness in these children have not been confirmed.

PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Augmentin Suspension while you are pregnant. Augmentin Suspension is found in breast milk. If you are or will be breast-feeding while you use Augmentin Suspension, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Augmentin Suspension:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; confusion; dark urine; fever, chills, or persistent sore throat; red, swollen, blistered, or peeling skin; seizures; severe diarrhea; stomach pain or cramps; unusual bruising or bleeding; vaginal discharge or irritation; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Augmentin side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include decreased urination; severe nausea, vomiting, or diarrhea; stomach pain; unusual drowsiness.

Proper storage of Augmentin Suspension:

Store Augmentin Suspension in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Do not store in the bathroom. Throw away any unused medicine after 10 days. Keep Augmentin Suspension out of the reach of children and away from pets.

General information:

If you have any questions about Augmentin Suspension, please talk with your doctor, pharmacist, or other health care provider.

Augmentin Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.

If your symptoms do not improve or if they become worse, check with your doctor.

Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Augmentin Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

More Augmentin resources

Augmentin Side Effects (in more detail)
Augmentin Use in Pregnancy & Breastfeeding
Drug Images
Augmentin Drug Interactions
Augmentin Support Group
55 Reviews for Augmentin - Add your own review/rating

Compare Augmentin with other medications

Aspiration Pneumonia
Bacterial Infection
Bronchitis
Febrile Neutropenia
Kidney Infections
Melioidosis
Otitis Media
Pneumonia
Sinusitis
Skin and Structure Infection
Skin Infection
Small Bowel Bacterial Overgrowth
Strep Throat
Upper Respiratory Tract Infection
Urinary Tract Infection

Saturday 15 September 2012

Meticorten

Generic Name: prednisone (PRED ni sone)

Brand Names: Sterapred, Sterapred DS

What is Meticorten (prednisone)?

Prednisone is a steroid. Prednisone prevents the release of substances in the body that cause inflammation.

Prednisone is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders.

Prednisone may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Meticorten (prednisone)?

You should not use this medication if you are allergic to prednisone, or if you have a fungal infection anywhere in your body.

Before taking prednisone, tell your doctor about all of your medical conditions, and about all other medicines you are using. There are many other diseases that can be affected by steroid use, and many other medicines that can interact with steroids.

Your dosage needs may change if you have any unusual stress such as a serious illness, fever or infection, or if you have surgery or a medical emergency. Tell your doctor about any such situation that affects you during treatment.

Steroid medication can weaken your immune system, making it easier for you to get an infection or worsening an infection you already have or have recently had. Tell your doctor about any illness or infection you have had within the past several weeks.

Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using a steroid.

Do not receive a "live" vaccine while using prednisone. The vaccine may not work as well during this time, and may not fully protect you from disease.

Wear a medical alert tag or carry an ID card stating that you take prednisone. Any medical care provider who treats you should know that you are using a steroid.

What should I discuss with my healthcare provider before taking Meticorten (prednisone)?

You should not use this medication if you are allergic to prednisone, or if you have a fungal infection anywhere in your body.

Steroid medicine can weaken your immune system, making it easier for you to get an infection. Steroids can also worsen an infection you already have, or reactivate an infection you recently had. Before taking this medication, tell your doctor about any illness or infection you have had within the past several weeks.

To make sure you can safely take prednisone, tell your doctor if you have any of these other conditions:

liver disease (such as cirrhosis);

kidney disease;

a thyroid disorder;

diabetes;

a history of malaria;

tuberculosis;

osteoporosis;

a muscle disorder such as myasthenia gravis;

glaucoma or cataracts;

herpes infection of the eyes;

stomach ulcers, ulcerative colitis, or diverticulitis;

depression or mental illness;

congestive heart failure; or

high blood pressure

It is not known whether prednisone will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Prednisone can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Steroids can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.

How should I take Meticorten (prednisone)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Take with food if prednisone upsets your stomach.

Your dosage needs may change if you have unusual stress such as a serious illness, fever or infection, or if you have surgery or a medical emergency. Tell your doctor about any such situation that affects you.

Measure liquid medicine with a special dose measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose measuring device, ask your pharmacist for one.

This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using prednisone.

Do not stop using prednisone suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Wear a medical alert tag or carry an ID card stating that you take prednisone. Any medical care provider who treats you should know that you are using a steroid. Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Long-term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while taking Meticorten (prednisone)?

Do not receive a "live" vaccine while taking prednisone. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), Bacillus Calmette-Guérin (BCG), oral polio, rotavirus, smallpox, typhoid, yellow fever, varicella (chickenpox), H1N1 influenza, and nasal flu vaccine.

Avoid drinking alcohol while you are taking prednisone.

Meticorten (prednisone) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

blurred vision, eye pain, or seeing halos around lights;

swelling, rapid weight gain, feeling short of breath;

severe depression, unusual thoughts or behavior, seizure (convulsions);

bloody or tarry stools, coughing up blood;

pancreatitis (severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate);

low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling); or

dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects may include:

sleep problems (insomnia), mood changes;

acne, dry skin, thinning skin, bruising or discoloration;

slow wound healing;

increased sweating;

headache, dizziness, spinning sensation;

nausea, stomach pain, bloating; or

changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Meticorten (prednisone)?

Many drugs can interact with prednisone. Below is just a partial list. Tell your doctor if you are using:

aspirin (taken on a daily basis or at high doses);

a diuretic (water pill);

a blood thinner such as warfarin (Coumadin, Jantoven);

cyclosporine (Gengraf, Neoral, Sandimmune);

insulin or diabetes medications you take by mouth;

ketoconazole (Nizoral);

rifampin (Rifadin, Rifater, Rifamate, Rimactane); or

seizure medications such as phenytoin (Dilantin) or phenobarbital (Luminal, Solfoton).

This list is not complete and other drugs may interact with prednisone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Meticorten resources

Meticorten Side Effects (in more detail)
Meticorten Use in Pregnancy & Breastfeeding
Meticorten Drug Interactions
Meticorten Support Group
1 Review for Meticorten - Add your own review/rating

Deltasone Prescribing Information (FDA)

Deltasone Advanced Consumer (Micromedex) - Includes Dosage Information

Prednisone Prescribing Information (FDA)

Prednisone Professional Patient Advice (Wolters Kluwer)

Prednisone Monograph (AHFS DI)

Prednisone MedFacts Consumer Leaflet (Wolters Kluwer)

Sterapred MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Meticorten with other medications

Acute Lymphocytic Leukemia
Adrenocortical Insufficiency
Adrenogenital Syndrome
Allergic Reactions
Ankylosing Spondylitis
Aspiration Pneumonia
Asthma
Atopic Dermatitis
Autoimmune Hemolytic Anemia
Berylliosis
Bullous Pemphigoid
Bursitis
Chorioretinitis
Cluster Headaches
Cogan's Syndrome
Conjunctivitis, Allergic
Corneal Ulcer
Dermatitis Herpetiformis
Dermatomyositis
Eczema
Epicondylitis, Tennis Elbow
Erythroblastopenia
Fibromyalgia
Gouty Arthritis
Graft-versus-host disease
Hay Fever
Herpes Zoster
Herpes Zoster Iridocyclitis
Hypercalcemia of Malignancy
Idiopathic Thrombocytopenic Purpura
Immunosuppression
Inflammatory Bowel Disease
Inflammatory Conditions
Iridocyclitis
Iritis
Juvenile Rheumatoid Arthritis
Keratitis
Leukemia
Lichen Planus
Lichen Sclerosus
Loeffler's Syndrome
Lymphoma
Multiple Sclerosis
Mycosis Fungoides
Nephrotic Syndrome
Neurosarcoidosis
Osteoarthritis
Pemphigoid
Pemphigus
Pharyngitis
Polymyositis/Dermatomyositis
Psoriasis
Psoriatic Arthritis
Rheumatoid Arthritis
Sarcoidosis
Seborrheic Dermatitis
Sinusitis
Skin Rash
Synovitis
Systemic Lupus Erythematosus
Systemic Sclerosis
Thrombocytopenia
Toxic Epidermal Necrolysis
Tuberculosis, Extrapulmonary
Tuberculous Meningitis
Ulcerative Colitis
Uveitis, Posterior

Where can I get more information?

Your pharmacist can provide more information about prednisone.

See also: Meticorten side effects (in more detail)

Sunday 9 September 2012

salicylic acid topical

Generic Name: salicylic acid topical (SAL i SIL ik AS id TOP ik al)

Brand names: Compound W, DermalZone, Dermarest Psoriasis Skin Treatment, Dr Scholl's Callus Removers, Dr Scholl's Clear Away Wart Remover, Dr Scholl's Corn Removers, Duofilm, Freezone Corn Remover, Hydrisalic, Keralyt, Mediplast, Oxy Face Scrub, Propa P.H., Salac, Salex, Scalpicin Scalp Relief, Sebucare, Stri-Dex, Wart-Off Treatment, ...show all 139 brand names.

What is salicylic acid topical?

Salicylic acid is a keratolytic (peeling agent). Salicylic acid causes shedding of the outer layer of skin.

Salicylic acid topical is used in the treatment of acne, dandruff, corns, and warts.

Salicylic acid topical may also be used for purposes other than those listed here.

What is the most important information I should know about salicylic acid topical?

Avoid the eyes, mouth, lips, inside the nose, genitals, and anal areas when applying salicylic acid topical. Do not use the wart remover on moles or birthmarks, or warts with hair growing from them, red edges, or unusual color. Also, do not use salicylic acid topical on sunburned, windburned, dry, chapped, irritated, or broken skin; or on open wounds. If medication is applied to any of these areas, wash with water.

What should I discuss with my healthcare provider before using salicylic acid topical?

Before using salicylic topical, talk to your doctor if you

have kidney disease;

have liver disease;

have diabetes;

have poor circulation; or

are treating a child.

You may not be able to use salicylic acid topical, or you may require a dosage adjustment or special monitoring during treatment.

It is not known whether salicylic acid topical will be harmful to an unborn baby. Do not use salicylic acid topical without first talking to your doctor if you are pregnant or could become pregnant during treatment. Salicylic acid topical may pass into breast milk and affect a nursing baby. Do not use salicylic acid topical without first talking to your doctor if you are breast-feeding a baby.

How should I use salicylic acid topical?

Use salicylic acid topical exactly as directed by your healthcare provider or as directed on the package. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Gently clean and dry the affected area. For the treatment of warts and calluses, gentle removal of loose skin with a soft brush, wash cloth, or emery board may be recommended before application of the medication.

Shake the lotion gently before application.

Apply a thin film of the medication to the affected area(s) as directed.

Use the soap and shampoo as directed on the package.

Apply the salicylic acid topical adhesive pads as directed on the package.

It is important to use salicylic acid topical regularly to get the most benefit. Do not stop using the medication if you do not see results immediately. Use the medication for the full amount of time directed.

Talk to your doctor if you experience excessive burning, dryness, or irritation of the skin, or changes in the color of the skin.

Store salicylic acid topical at room temperature away from moisture and heat. Some forms of salicylic acid topical may be flammable, keep away from heat and flame.

What happens if I miss a dose?

Use the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and use only the next regularly scheduled dose.

Do not apply a double dose of the medication.

What happens if I overdose?

An overdose of salicylic acid topical is unlikely to occur. If you do suspect an overdose, or if the medication has been ingested, call a poison control center or emergency room for advice.

What should I avoid while using salicylic acid topical?

Do not use other topical preparations on the treated area unless otherwise directed by your healthcare provider. They may interfere with treatment or increase skin irritation.

Avoid the use of abrasive, harsh, or drying soaps and cleansers such as alcoholic cleansers, tinctures, astringents, abrasives, or other peeling agents while using salicylic acid topical.

Salicylic acid topical side effects

Serious side effects are not likely to occur with the use of salicylic acid topical. If you do experience any of the following rare serious side effects, stop using salicylic acid topical and seek emergency medical attention or contact your doctor:

an allergic reaction (shortness of breath; closing of the throat; swelling of the lips, face, or tongue; or hives); or

severe skin irritation.

Other, less serious side effects are more likely to occur. Continue to use salicylic acid topical and talk to your doctor if you experience skin burning; stinging; itching; dryness; redness; peeling; or irritation.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

Salicylic acid topical Dosing Information

Usual Adult Dose for Acne:

Salicylic acid topical 1% pad:
Cleanse affected area. Apply 2 to 3 times daily. If dryness occurs, reduce to every other or once a day.

Usual Adult Dose for Dermatological Disorders:

Salicylic acid topical 16.7% liquid:
Wash and dry area thoroughly. Apply enough to cover each wart 1 to 2 times daily.

Salicylic acid 3% topical soap:
Apply to affect areas at least twice weekly. Leave lather on scalp or skin for two minutes then rinse. Repeat if necessary.

Salicylic acid topical 6% cream:
Apply to affected area once daily. Hydrate area for 5 minutes prior to application if possible. Occlude the area at night. Wash off in morning.

Salicylic acid topical 6% lotion:
Apply to affected area once daily. Hydrate area for 5 minutes prior to application if possible. Occlude the area at night. Wash off in morning.

Salicylic acid topical 6% foam:
Apply to affected area once daily at bedtime. Hydrate area for 5 minutes prior to application if possible. Occlude the area after application. Wash off in morning.

Usual Pediatric Dose for Acne:

Salicylic acid topical 1% pad:
12 years or older: Cleanse affected area. Apply 2 to 3 times daily. If dryness occurs, reduce to every other or once a day.

What other drugs will affect salicylic acid topical?

Do not use other topical preparations on the treated area unless otherwise directed by your healthcare provider. They may interfere with treatment or increase skin irritation.

Avoid the use of abrasive, harsh, or drying soaps and cleansers such as alcoholic cleansers, tinctures, astringents, abrasives, or other peeling agents while using salicylic acid topical.

Drugs other than those listed here may also interact with salicylic acid topical. Talk to your doctor and pharmacist before taking or using any other prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Compare salicylic acid topical with other medications

Acne
Dermatological Disorders
Warts

Where can I get more information?

Your pharmacist has additional information about salicylic acid topical written for health professionals that you may read.

See also: salicylic acid side effects (in more detail)

Friday 7 September 2012

Ucephan

Generic Name: sodium benzoate and sodium phenylacetate (Oral route)

SOE-dee-um BEN-zoe-ate, SOE-dee-um fen-il-AS-e-tate

Commonly used brand name(s)

In the U.S.

Ucephan

Available Dosage Forms:

Solution

Therapeutic Class: Hyperammonemia Agent

Uses For Ucephan

Sodium benzoate and sodium phenylacetate combination is used to treat a condition caused by too much ammonia in the blood (hyperammonemia). This medicine works by causing less ammonia to be produced by the body.

Ammonia is formed from the breakdown of protein in the body. If the ammonia cannot be removed by the body, then a buildup may cause serious unwanted effects.

Sodium benzoate and sodium phenylacetate combination is available only with your doctor's prescription.

Before Using Ucephan

Allergies

Pediatric

This medicine has been tested in children and, in effective doses, has not been shown to cause different side effects or problems than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing the use of sodium benzoate and sodium phenylacetate in the elderly with use in other age groups.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Proper Use of Ucephan

It is important that you follow any special instructions from your doctor, such as following a low protein diet. If you have any questions about this, check with your doctor.

Dosing

For injection dosage form (solution):
- Treatment of too much ammonia in the blood:
  - Adults and children—The dose is based on body weight and must be determined by the doctor.

Missed Dose

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Ucephan

Your doctor should check your progress at regular visits to make sure that this medicine is working properly.

Ucephan Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Stop taking this medicine and get emergency help immediately if any of the following effects occur:

More common

Confusion

convulsions

decreased urine

dry mouth

headache

increase in frequency of seizures

increased thirst

irregular heartbeat

loss of appetite

mood changes

muscle pain or cramps

nausea

numbness or tingling in hands, feet, or lips

problems with movement, walking or speech

shortness of breath

swelling of face

unusual tiredness or weakness

vomiting

yellow eyes or skin

Less common

Blood in stools

blood in urine

bruising

change in consciousness

coughing or vomiting blood

difficulty in breathing

drowsiness

loss of consciousness

mental changes

muscle cramps in hands, arms, feet, legs, or face

muscle tremors

persistent bleeding or oozing from puncture sites, mouth, or nose

rapid, deep breathing

rash

restlessness

shortness of breath

stomach cramps

tightness in chest

tremor

troubled breathing

wheezing

Frequency unknown

Abnormally slow deep breathing

blue lips, fingernails, or skin

blurred vision

bulging soft spot on head of an infant

change in ability to see colors, especially blue or yellow

chest pain or discomfort

dizziness or fainting

injection site hemorrhage

insomnia

irregular, fast or slow, or shallow breathing

lightheadedness

severe headache

shakiness

sleepiness

slow heartbeat

slow to respond

slurred speech

unconsciousness

Symptoms of overdose

Agitation

back pain

blue lips, fingernails, or skin

blurred vision

bulging soft spot on head of an infant

change in ability to see colors, especially blue or yellow

chest pain or discomfort

chills

cold, clammy, pale skin

coma

confusion

continuing nausea or vomiting

cough

deep or fast breathing with dizziness

difficult or troubled breathing

dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly

drowsiness

fainting

fast heartbeat

fever

general feeling of discomfort or illness

hallucinations

headache

high blood pressure

insomnia

irregular, fast or slow, or shallow breathing

irregular heartbeats

irritability

lightheadedness

loss of appetite

mood or mental changes

muscle twitching

no blood pressure

not alert

numbness to feet, hands and around mouth

rapid, shallow breathing

restlessness

seizures

slow heart rate

stiff neck

sweating

swelling of face

swelling of feet or lower legs

thickening of bronchial secretions

trouble with coordination

unusual tiredness or weakness

vomiting

weakness

yellow eyes or skin

More common

Changes in skin color

cold hands and feet

confusion or excitement

cough or hoarseness;

dry mouth;

fever or chills

flushed, dry skin;

fruit-like breath odor

increased hunger

increased thirst

increased urination

lower back or side pain

mental depression or anxiety

nightmares or unusually vivid dreams

painful or difficult urination

pain, redness, or swelling in arm or leg

skin disorders

sweating

unexplained weight loss

Less common

Bladder pain

bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection; inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at site

decrease in urine-concentrating ability

diarrhea

difficult, burning, or painful urination

frequent urge to urinate

hyperventilation

nervousness

pale skin

shaking

troubled breathing with exertion

trouble sleeping

unusual bleeding or bruising

Frequency unknown

Blister

full or bloated feeling or pressure in the stomach

itching skin

rash with flat lesions or small raised lesions on the skin

swelling of abdominal or stomach area

uncontrolled jerking movement

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

More Ucephan resources

Ucephan Use in Pregnancy & Breastfeeding
Ucephan Drug Interactions
Ucephan Support Group
0 Reviews for Ucephan - Add your own review/rating

Compare Ucephan with other medications

Hyperammonemia